Cifani lab

Panepinto, Maria C, Minicozzi, Francesca , Cifani, Paolo (2025) High Dynamic Range Peptide Mass Spectrometry Using Segmented Precursor Ion Accumulation. Analytical Chemistry

Improved dynamic range and sensitivity in MS1 scans using gas-phase fractionation. No cost approach to enhance sensitivity of MS1 detection (and quantification) and precursor sampling in DDA mode.

Shared Resource (selected)

Garg, Ankur, On, Kin Fan, Xiao, Yang, Elkayam, Elad, Cifani, Paolo, David, Yael , Joshua-Tor, Leemor (2025) The molecular basis of Human FN3K mediated phosphorylation of glycated substrates. Nature Communications, 16(1) pp. 941.

We used intact protein measurements to quantify glycation.

Swamynathan, Manojit M, Kuang, Shan, Watrud, Kaitlin E, Doherty, Mary R, Gineste, Charlotte, Mathew, Grinu, Gong, Grace Q, Cox, Hilary, Cheng, Eileen, Reiss, David, Kendall, Jude, Ghosh, Diya, Reczek, Colleen R, Zhao, Xiang, Herzka, Tali, Špokaitė, Saulė, Dessus, Antoine N, Kim, Seung Tea, Klingbeil, Olaf, Liu, Juan, Nowak, Dawid G, Alsudani, Habeeb, Wee, Tse-Luen, Park, Youngkyu, Minicozzi, Francesca, Rivera, Keith, Almeida, Ana S, Chang, Kenneth, Chakrabarty, Ram P, Wilkinson, John E, Gimotty, Phyllis A, Diermeier, Sarah D, Egeblad, Mikala, Vakoc, Christopher R, Locasale, Jason W, Chandel, Navdeep S, Janowitz, Tobias, Hicks, James B, Wigler, Michael, Pappin, Darryl J, Williams, Roger L, Cifani, Paolo, Tuveson, David A, Laporte, Jocelyn , Trotman, Lloyd C (2024) Dietary pro-oxidant therapy by a vitamin K precursor targets PI 3-kinase VPS34 function. Science, 386(6720) pp. eadk9167.

Sequential alkylation strategy to measure differential stoichiometry of cysteine oxidation.

Yang, Xiaochun, Bhowmick, Krishanu, Rao, Shuyun, Xiang, Xiyan, Ohshiro, Kazufumi, Amdur, Richard L, Hassan, Md Imtaiyaz, Mohammad, Taj, Crandall, Keith, Cifani, Paolo, Shetty, Kirti, Lyons, Scott K, Merrill, Joseph R, Vegesna, Anil K, John, Sahara, Latham, Patricia S, Crawford, James M, Mishra, Bibhuti, Dasarathy, Srinivasan, Wang, Xin Wei, Yu, Herbert, Wang, Zhanwei, Huang, Hai, Krainer, Adrian R , Mishra, Lopa (2024) Aldehydes alter TGF-β signaling and induce obesity and cancer. Cell Reports, 43(9) pp. 114676.

MS measurements of 4-HNE adducts. 

Klingbeil, OlafSkopelitis, DamianosTonelli, ClaudiaYoshimoto, ToyokiAlpsoy, AktanPanepinto, Maria CMinicozzi, FrancescaMerrill, Joseph RCafiero, Amanda MAggarwal, DishaRusso, SuzanneHa, TaehoonDemerdash, Osama EWee, Tse-LuenSpector, David LLyons, Scott KTuveson, David ACifani, PaoloVakoc, Christopher R (July 2024) MARK2/MARK3 kinases are catalytic co-dependencies of YAP/TAZ in human cancer. Cancer Discovery. ISSN 2159-8274 .

In-depth mapping of kinase activity.

All publications (automatically populated)

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